Storage Conditions
-20°C/1 year
Applications
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SIK. AA range:148-197
Subcellular Location
Cytoplasm . Nucleus . Locates to cytoplasm when inactive following cAMP-induced phosphorylation, probably by PKA (PubMed:29211348).
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Rat
Human Gen
150094
Observed Band
85kD
Other Name
SIK
SIK-1
SIK1
SNF1LK
Salt-inducible kinase 1
Serine/threonine-protein kinase SIK1
Serine/threonine-protein kinase SNF1-like kinase 1
Serine/threonine-protein kinase SNF1LK
Background
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-182 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Transient role