Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human n-ternal COL17A1 . at AA range: 1-80
Subcellular Location
Cell junction, hemidesmosome. Membrane
Single-pass type II membrane protein. Localized along the plasma membrane of the hemidesmosome.
[97 kDa linear IgA disease antigen]: Secreted, extracellular space, extracellular matrix, basement membrane. Localized in the lamina lucida beneath the hemidesmosomes.
[120 kDa linear IgA disease antigen]: Secreted, extracellular space, extracellular matrix, basement membrane. Exclusively localized to anchoring filaments. Localized to the epidermal side of split skin.
Single-pass type II membrane protein. Localized along the plasma membrane of the hemidesmosome.
[97 kDa linear IgA disease antigen]: Secreted, extracellular space, extracellular matrix, basement membrane. Localized in the lamina lucida beneath the hemidesmosomes.
[120 kDa linear IgA disease antigen]: Secreted, extracellular space, extracellular matrix, basement membrane. Exclusively localized to anchoring filaments. Localized to the epidermal side of split skin.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
1308
Other Name
180 kDa bullous pemphigoid antigen 2
BP180
BPAG2
Bullous pemphigoid antigen 2
COL17A1
Collagen alpha-1(XVII) chain
BP180
BPAG2
Bullous pemphigoid antigen 2
COL17A1
Collagen alpha-1(XVII) chain
Background
This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that