Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ACTR-1C. AA range:201-250
Subcellular Location
Membrane
Single-pass type I membrane protein .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
130399
Other Name
ACTR-IC
ACVR1C
ALK-7
ALK7
Activin receptor-like kinase 7
Activin receptor type-1C
Activin receptor type IC
Background
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in