Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ABCC2. AA range:991-1040
Subcellular Location
Apical cell membrane
Multi-pass membrane protein .
Multi-pass membrane protein .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
1244
Observed Band
175kD
Other Name
ABCC2
ATP-binding cassette sub-family C member 2
CMOAT
CMOAT1
CMRP
Canalicular multidrug resistance protein
Canalicular multispecific organic anion transporter 1
MRP2
Multidrug resistance-associated protein 2
ATP-binding cassette sub-family C member 2
CMOAT
CMOAT1
CMRP
Canalicular multidrug resistance protein
Canalicular multispecific organic anion transporter 1
MRP2
Multidrug resistance-associated protein 2
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, M
therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyp
therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyp