Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from MAN1B1 . at AA range: 100-180
Subcellular Location
Endoplasmic reticulum membrane
Single-pass type II membrane protein .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
11253
Observed Band
80kD
Other Name
2-alpha-mannosidase
ERMan1
ER alpha-1,2-mannosidase
ER mannosidase 1
Endoplasmic reticulum mannosyl-oligosaccharide 1
MAN1B1
Man9GlcNAc2-specific-processing alpha-mannosidase
Mannosidase alpha class 1B member 1
Background
This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan tri