Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the N-terminal region of human Calpain 10.
Subcellular Location
intracellular,cell,mitochondrion,cytosol,plasma membrane,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
11132
Observed Band
75kD
Other Name
CANP 10
CAPN10
Calcium-activated neutral proteinase 10
Calpain-10
KIAA1845
CAPN10
Calcium-activated neutral proteinase 10
Calpain-10
KIAA1845
Background
Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domai
and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organizatio
domain II, the protease domain
domain III, a linker domain of unknown function
and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organizatio
domain II, the protease domain
domain III, a linker domain of unknown function