Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human IGF2BP2. AA range:141-190
Subcellular Location
Nucleus. Cytoplasm. Cytoplasm, P-body . Cytoplasm, Stress granule . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Localizes at the connecting piece and the tail of the spermatozoa. In response to cellular stress, such as oxidative
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
10644
Observed Band
65kD
Other Name
Hepatocellular carcinoma autoantigen p62
IGF-II mRNA-binding protein 2
IGF2 mRNA-binding protein 2
IGF2BP2
IMP-2
IMP2
Insulin-like growth factor 2 mRNA-binding protein 2
VICKZ2
VICKZ family member 2
IGF-II mRNA-binding protein 2
IGF2 mRNA-binding protein 2
IGF2BP2
IMP-2
IMP2
Insulin-like growth factor 2 mRNA-binding protein 2
VICKZ2
VICKZ family member 2
Background
This gene encodes a protein that binds the 5' UTR of insulin-like growth factor 2 (IGF2) mRNA and regulates its translation. It plays an important role in metabolism and variation in this gene is associated with susceptibility to diabetes. Alternative spl