Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SLC9A6. AA range:551-600
Subcellular Location
Endosome membrane
Multi-pass membrane protein .
Multi-pass membrane protein . Is present in the recycling compartments including early and recycling endosomes, and only appears transiently on the plasma membrane.
[Isoform 2]: Recycling endosome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
10479
Observed Band
75kD
Other Name
KIAA0267
NHE-6
NHE6
Na(+)/H(+) exchanger 6
SLC9A6
Sodium/hydrogen exchanger 6
Solute carrier family 9 member 6
Background
This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated wit