Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized phospho-peptide around the phosphorylation site of human Vav3 (phospho Tyr173)
Subcellular Location
intracellular,cytosol,plasma membrane,extracellular exosome,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
10451
Observed Band
100kD
Other Name
Guanine nucleotide exchange factor VAV3
VAV-3
VAV3
Background
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product act