Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
IF
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human KNTC2. AA range:351-400
Subcellular Location
Nucleus . Chromosome, centromere, kinetochore . Localizes to kinetochores from late prophase to anaphase (PubMed:14699129). Localizes specifically to the outer plate of the kinetochore (PubMed:14699129). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
10403
Observed Band
73kD
Other Name
HEC
HEC1
Highly expressed in cancer protein
HsHec1
KNTC2
Kinetochore-associated protein 2
Kinetochore protein Hec1
Kinetochore protein NDC80 homolog
NDC80
Retinoblastoma-associated protein HEC
HEC1
Highly expressed in cancer protein
HsHec1
KNTC2
Kinetochore-associated protein 2
Kinetochore protein Hec1
Kinetochore protein NDC80 homolog
NDC80
Retinoblastoma-associated protein HEC
Background
This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to o