Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
Concentration
1 mg/ml
Recomended Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the Internal region of human USP11.
Subcellular Location
Nucleus . Cytoplasm . Chromosome . Predominantly nuclear (PubMed:12084015, PubMed:15314155). Associates with chromatin (PubMed:20601937, PubMed:20233726). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
8237
Observed Band
105kD
Other Name
Deubiquitinating enzyme 11
UHX1
USP11
Ubiquitin-specific-processing protease 11
Ubiquitin carboxyl-terminal hydrolase 11
Ubiquitin thioesterase 11
Background
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and remov