Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from mouse FADD around the phosphorylation site of Ser191. AA range:157-206
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Mouse
Observed Band
25kD
Other Name
FADD
FAS-associated death domain protein
FAS-associating death domain-containing protein
GIG3
Growth-inhibiting gene 3 protein
MORT1
Mediator of receptor induced toxicity
Protein FADD
Background
The Fas associated via death domain encoded by FADD is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor,