Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human AICDA. AA range:81-130
Subcellular Location
Nucleus . Cytoplasm . Predominantly cytoplasmic (PubMed:21385873). In the presence of MCM3AP/GANP, relocalizes to the nucleus (By similarity). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
57379
Observed Band
24kD
Other Name
AICDA
AID
Activation-induced cytidine deaminase
Cytidine aminohydrolase
AID
Activation-induced cytidine deaminase
Cytidine aminohydrolase
Background
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of a