Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human IL6R. AA range:221-270
Subcellular Location
Single-pass type I membrane protein .
[Isoform 1]: Cell membrane
[Isoform 2]: Secreted .
[Soluble interleukin-6 receptor subunit alpha]: Secreted .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
3570
Observed Band
53kD
Other Name
CD126
IL-6 receptor subunit alpha
IL-6R-alpha
IL-6R 1
IL-6RA
IL-6R subunit alpha
IL6R
Interleukin-6 receptor subunit alpha
Membrane glycoprotein 80
gp80
Background
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein comple