Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human TERT. AA range:931-980
Subcellular Location
Nucleus, nucleolus . Nucleus, nucleoplasm. Nucleus. Chromosome, telomere. Cytoplasm. Nucleus, PML body. Shuttling between nuclear and cytoplasm depends on cell cycle, phosphorylation states, transformation and DNA damage. Diffuse localization in the nucle
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
7015
Observed Band
130kD
Other Name
EST2
HEST2
TCS1
TERT
TP2
TRT
Telomerase-associated protein 2
Telomerase catalytic subunit
Telomerase reverse transcriptase
HEST2
TCS1
TERT
TP2
TRT
Telomerase-associated protein 2
Telomerase catalytic subunit
Telomerase reverse transcriptase
Background
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as
the full-length sequence of some variants has not been determined. Alternative sp
the full-length sequence of some variants has not been determined. Alternative sp