Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human IL36B. AA range:111-160
Subcellular Location
Cytoplasm . Secreted . The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10
it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. .
it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
27177
Observed Band
19kD
Other Name
FIL1 eta
IL-1 eta
IL-1F8
IL-1H2
IL1F8
IL1H2
IL36B
Interleukin-1 eta
Interleukin-1 family member 8
Interleukin-1 homolog 2
Interleukin-36 beta
IL-1 eta
IL-1F8
IL-1H2
IL1F8
IL1H2
IL36B
Interleukin-1 eta
Interleukin-1 family member 8
Interleukin-1 homolog 2
Interleukin-36 beta
Background
The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). T