Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the Internal region of human NCoA-3.
Subcellular Location
Cytoplasm. Nucleus. Mainly cytoplasmic and weakly nuclear. Upon TNF activation and subsequent phosphorylation, it translocates from the cytoplasm to the nucleus.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
8202
Observed Band
160kD
Other Name
ACTR
AIB-1
AIB1
Amplified in breast cancer 1 protein
BHLHE42
CBP-interacting protein
Class E basic helix-loop-helix protein 42
NCOA3
NCoA-3
Nuclear receptor coactivator 3
RAC-3
RAC3
Receptor-associated coactivator 3
SRC-3
Steroid receptor coactivator protein 3
TRAM-1
TRAM1
Thyroid hormone receptor activator molecule 1
bHLHe42
pCIP
Background
The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associa