Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human HLA-DQB1/HLA-DQB2. AA range:131-180
Subcellular Location
Cell membrane
Single-pass type I membrane protein. Endoplasmic reticulum membrane
Single-pass type I membrane protein. Endosome membrane
Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane
Single-pass type I membrane protein. Lysosome membrane
Single-pass type I membrane protein. The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Human Gen
100507714
Observed Band
30kD
Other Name
HLA-DQB
HLA-DQB1
HLA-DQB2
HLA-DXB
HLA class II histocompatibility antigen, DQ beta 1 chain
HLA class II histocompatibility antigen, DQ beta 2 chainHLA class II histocompatibility antigen, DX beta chain
MHC class II antigen DQB1
MHC class II antigen DQB2
Background
major histocompatibility complex, class II, DQ beta 1(HLA-DQB1) Homo sapiens HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the mem