Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CRHR1. AA range:71-120
Subcellular Location
Cell membrane
Multi-pass membrane protein. Endosome. Agonist-binding promotes endocytosis.
Multi-pass membrane protein. Endosome. Agonist-binding promotes endocytosis.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
1394
Observed Band
50kD
Other Name
CRF-R-1
CRF-R1
CRFR
CRFR-1
CRFR1
CRH-R-1
CRH-R1
CRHR
CRHR1
Corticotropin-releasing factor receptor 1
Corticotropin-releasing hormone receptor 1
CRF-R1
CRFR
CRFR-1
CRFR1
CRH-R-1
CRH-R1
CRHR
CRHR1
Corticotropin-releasing factor receptor 1
Corticotropin-releasing hormone receptor 1
Background
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal tr