Información del producto
STING/TMEM173 rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from Transmembrane protein 173 at AA range: 301-350
Subcellular Location
Endoplasmic reticulum membrane
Multi-pass membrane protein . Cell membrane
Multi-pass membrane protein . Cytoplasm, perinuclear region . Endoplasmic reticulum-Golgi intermediate compartment membrane
Multi-pass membrane protein . Cytoplasmic vesicle, autophagosome membrane
Multi-pass membrane protein . Golgi apparatus membrane
Multi-pass membrane protein . In response to double-stranded DNA stimulation, translocates from the endoplasmic reticulum through the endoplasmic reticulum-Golgi intermediate compartment and Golgi to post-Golgi vesicles, where the kinase TBK1 is recruited
Multi-pass membrane protein . Mitochondrion outer membrane
Multi-pass membrane protein . Cell membrane
Multi-pass membrane protein . Cytoplasm, perinuclear region . Endoplasmic reticulum-Golgi intermediate compartment membrane
Multi-pass membrane protein . Cytoplasmic vesicle, autophagosome membrane
Multi-pass membrane protein . Golgi apparatus membrane
Multi-pass membrane protein . In response to double-stranded DNA stimulation, translocates from the endoplasmic reticulum through the endoplasmic reticulum-Golgi intermediate compartment and Golgi to post-Golgi vesicles, where the kinase TBK1 is recruited
Multi-pass membrane protein . Mitochondrion outer membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
340061
Observed Band
38kD
Other Name
ERIS
ERIS
Endoplasmic reticulum interferon stimulator
MITA
Mediator of IRF3 activation
STING
Stimulator of interferon genes protein
TMEM173
Transmembrane protein 173
hMITA
hSTING
ERIS
Endoplasmic reticulum interferon stimulator
MITA
Mediator of IRF3 activation
STING
Stimulator of interferon genes protein
TMEM173
Transmembrane protein 173
hMITA
hSTING
Background
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits si