Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human F11R. AA range:191-240
Subcellular Location
Cell junction, tight junction . Cell membrane
Single-pass type I membrane protein . Localized at tight junctions of both epithelial and endothelial cells. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Rat
Human Gen
50848
Observed Band
32kD
Other Name
CD321
F11R
JAM-1
JAM-A
JAM1
JCAM
Junctional adhesion molecule 1
Junctional adhesion molecule A
PAM-1
Platelet F11 receptor
Platelet adhesion molecule 1
Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space.