Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CD74. AA range:161-210
Subcellular Location
Cell membrane
Single-pass type II membrane protein . Endoplasmic reticulum membrane. Golgi apparatus, trans-Golgi network. Endosome. Lysosome. Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach t
[Isoform p41]: Late endosome . Lysosome .
Single-pass type II membrane protein . Endoplasmic reticulum membrane. Golgi apparatus, trans-Golgi network. Endosome. Lysosome. Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach t
[Isoform p41]: Late endosome . Lysosome .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
972
Observed Band
33kD
Other Name
CD74
CD74
DHLAG
HLA-DR antigens-associated invariant chain
HLA class II histocompatibility antigen gamma chain
Ia antigen-associated invariant chain
Ii
p33
CD74
DHLAG
HLA-DR antigens-associated invariant chain
HLA class II histocompatibility antigen gamma chain
Ia antigen-associated invariant chain
Ii
p33
Background
The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage mig