Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human FOXP3. AA range:381-430
Subcellular Location
Nucleus . Cytoplasm . Predominantly expressed in the cytoplasm in activated conventional T-cells whereas predominantly expressed in the nucleus in regulatory T-cells (Treg). The 41 kDa form derived by proteolytic processing is found exclusively in the chr
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Pig
Rat
Mouse
Pig
Rat
Human Gen
50943
Observed Band
47kD
Other Name
FOXP3
Forkhead box protein P3
IPEX
JM2
Scurfin
Forkhead box protein P3
IPEX
JM2
Scurfin
Background
The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoim