Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human BMAL1 around the non-acetylation site of Lys538. AA range:501-550
Subcellular Location
Nucleus . Cytoplasm . Nucleus, PML body . Shuttles between the nucleus and the cytoplasm and this nucleocytoplasmic shuttling is essential for the nuclear accumulation of CLOCK, target gene transcription and the degradation of the CLOCK-ARNTL/BMAL1 hetero
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
406
Observed Band
69kD
Other Name
ARNTL
Aryl hydrocarbon receptor nuclear translocator-like protein 1
BHLHE5
BMAL1
Basic-helix-loop-helix-PAS protein MOP3
Brain and muscle ARNT-like 1Class E basic helix-loop-helix protein 5
MOP3
Member of PAS protein 3
PASD3
PAS domain-containing protein 3
bHLH-PAS protein JAP3
bHLHe5
Aryl hydrocarbon receptor nuclear translocator-like protein 1
BHLHE5
BMAL1
Basic-helix-loop-helix-PAS protein MOP3
Brain and muscle ARNT-like 1Class E basic helix-loop-helix protein 5
MOP3
Member of PAS protein 3
PASD3
PAS domain-containing protein 3
bHLH-PAS protein JAP3
bHLHe5
Background
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription