Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human TNFSF11. AA range:268-317
Subcellular Location
Single-pass type II membrane protein.
Single-pass type II membrane protein.
[Isoform 1]: Cell membrane
[Isoform 2]: Cytoplasm .
[Isoform 3]: Cell membrane
[Tumor necrosis factor ligand superfamily member 11, soluble form]: Secreted .
Single-pass type II membrane protein.
[Isoform 1]: Cell membrane
[Isoform 2]: Cytoplasm .
[Isoform 3]: Cell membrane
[Tumor necrosis factor ligand superfamily member 11, soluble form]: Secreted .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
8600
Observed Band
35kD
Other Name
CD254
ODF
OPGL
OPGLReceptor activator of nuclear factor kappa-B ligand
Osteoclast differentiation factor
Osteoprotegerin ligand
RANKL
RANKL
TNF-related activation-induced cytokine
TNFSF11
TRANCE
TRANCE
Tumor necrosis factor ligand superfamily member 11
ODF
OPGL
OPGLReceptor activator of nuclear factor kappa-B ligand
Osteoclast differentiation factor
Osteoprotegerin ligand
RANKL
RANKL
TNF-related activation-induced cytokine
TNFSF11
TRANCE
TRANCE
Tumor necrosis factor ligand superfamily member 11
Background
This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor