Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human NLRP3. AA range:511-560
Subcellular Location
Cytoplasm, cytosol . Inflammasome . Endoplasmic reticulum . Secreted . Nucleus . In macrophages, under resting conditions, mainly located in the cytosol, on the endoplasmic reticulum. After stimulation with inducers of the NLRP3 inflammasome, mitochondria
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
114548
Observed Band
115kD
Other Name
Angiotensin/vasopressin receptor AII/AVP-like
C1orf7
CIAS1
Caterpiller protein 1.1CLR1.1
Cold autoinflammatory syndrome 1 protein
Cryopyrin
NACHT, LRR and PYD domains-containing protein 3
NALP3
NLRP3
PYPAF1
PYRIN-containing APAF1-like protein 1
C1orf7
CIAS1
Caterpiller protein 1.1CLR1.1
Cold autoinflammatory syndrome 1 protein
Cryopyrin
NACHT, LRR and PYD domains-containing protein 3
NALP3
NLRP3
PYPAF1
PYRIN-containing APAF1-like protein 1
Background
This gene encodes a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase r