Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 1:5000-20000
IF/ICC 1:100-500
IHC-p 1:100-500
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human NFATC1. AA range:881-930
Subcellular Location
Cytoplasm . Nucleus . Cytoplasmic for the phosphorylated form and nuclear after activation that is controlled by calcineurin-mediated dephosphorylation. Rapid nuclear exit of NFATC is thought to be one mechanism by which cells distinguish between sustaine
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
4772
Observed Band
105kD
Other Name
NF-ATc
NF-ATc1
NFAT2
NFATC
NFATC1
NFATc
NFATc1
NFAT transcription complex cytosolic component
Nuclear factor of activated T-cells, cytoplasmic 1
Background
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor