Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human BAG1. AA range:41-90
Subcellular Location
[Isoform 1]: Nucleus. Cytoplasm. Isoform 1 localizes predominantly to the nucleus.
[Isoform 2]: Cytoplasm. Nucleus. Isoform 2 localizes to the cytoplasm and shuttles into the nucleus in response to heat shock.
[Isoform 4]: Cytoplasm. Nucleus. Isoform 4 localizes predominantly to the cytoplasm. The cellular background in which it is expressed can influence whether it resides primarily in the cytoplasm or is also found in the nucleus. In the presence of BCL2, loc
[Isoform 2]: Cytoplasm. Nucleus. Isoform 2 localizes to the cytoplasm and shuttles into the nucleus in response to heat shock.
[Isoform 4]: Cytoplasm. Nucleus. Isoform 4 localizes predominantly to the cytoplasm. The cellular background in which it is expressed can influence whether it resides primarily in the cytoplasm or is also found in the nucleus. In the presence of BCL2, loc
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
573
Observed Band
35kD
Other Name
BAG-1
BAG1
BAG family molecular chaperone regulator 1
Bcl-2-associated athanogene 1
HAP
BAG1
BAG family molecular chaperone regulator 1
Bcl-2-associated athanogene 1
HAP
Background
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects