Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human MME. AA range:491-540
Subcellular Location
Cell membrane
Single-pass type II membrane protein.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
4311
Observed Band
85kD
Other Name
Atriopeptidase
CALLA
CD10
Common acute lymphocytic leukemia antigen
EPN
Enkephalinase
MME
NEP
Neprilysin
Neutral endopeptidase
Neutral endopeptidase 24.11
SFE
Skin fibroblast elastase
Background
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases o