Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the C-terminal region of human Amphiphysin II.
Subcellular Location
[Isoform BIN1]: Nucleus . Cytoplasm . Endosome . Cell membrane, sarcolemma, T-tubule .
[Isoform IIA]: Cytoplasm .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Mouse
Rat
Human Gen
274
Observed Band
64kD
Other Name
AMPHL
Amphiphysin-like protein
Amphiphysin II
BIN1
Box-dependent myc-interacting protein 1
Bridging integrator 1
Myc box-dependent-interacting protein 1
Background
This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in