Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human SIGLEC8. AA range:81-130
Subcellular Location
Membrane
Single-pass type I membrane protein.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
27181
Observed Band
50kD
Other Name
CD329
CDw329
SAF-2
SAF2
SIGLEC8
Sialic acid-binding Ig-like lectin 8
Sialoadhesin family member 2
Siglec-8
Background
MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).[supplied by OMIM, May 2010],
MIM 603492) that mediates an association with SLAM-associated protein (SAP
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup o