Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CD59. AA range:51-100
Subcellular Location
Cell membrane
Lipid-anchor, GPI-anchor. Secreted. Soluble form found in a number of tissues.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
966
Observed Band
16kD
Other Name
1F5 antigen
20 kDa homologous restriction factor
CD59
CD59
CD59 glycoprotein
HRF-20
HRF20
MAC-IP
MAC-inhibitory protein
MACIF
MEM43 antigen
MIC11
MIN1
MIN2
MIN3
MIRL
MSK21
Membrane attack complex inhibition factor
Membrane inhibitor of reactive lysis
Protectin
Background
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8