Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the C-terminal region of human CD1E. AA range:321-370
Subcellular Location
Single-pass type I membrane protein. Early endosome. Late endosome. Predominantly localized in the trans-Golgi network in immature dendritic cells, and as a cleaved, soluble protein in the lysosome lumen of mature dendritic cells.
[T-cell surface glycoprotein CD1e, membrane-associated]: Golgi apparatus membrane
[T-cell surface glycoprotein CD1e, soluble]: Lysosome lumen.
[T-cell surface glycoprotein CD1e, membrane-associated]: Golgi apparatus membrane
[T-cell surface glycoprotein CD1e, soluble]: Lysosome lumen.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
913
Observed Band
42kD
Other Name
CD1E
CD1e
R2G1
T-cell surface glycoprotein CD1e, membrane-associated
hCD1e
CD1e
R2G1
T-cell surface glycoprotein CD1e, membrane-associated
hCD1e
Background
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation o