Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human INPPL1. AA range:351-400
Subcellular Location
Cytoplasm, cytosol . Cytoplasm, cytoskeleton. Membrane
Peripheral membrane protein. Cell projection, filopodium . Cell projection, lamellipodium . Nucleus . Nucleus speckle . Translocates to membrane ruffles when activated, translocation is probably due to different mechanisms depending on the stimulus and ce
Peripheral membrane protein. Cell projection, filopodium . Cell projection, lamellipodium . Nucleus . Nucleus speckle . Translocates to membrane ruffles when activated, translocation is probably due to different mechanisms depending on the stimulus and ce
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
3636
Observed Band
130kD
Other Name
INPPL-1
INPPL1
Inositol polyphosphate phosphatase-like protein 1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
Protein 51C
SH2 domain-containing inositol 5'-phosphatase 2
SH2 domain-containing inositol phosphatase 2
SHIP-2
SHIP2
INPPL1
Inositol polyphosphate phosphatase-like protein 1
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
Protein 51C
SH2 domain-containing inositol 5'-phosphatase 2
SH2 domain-containing inositol phosphatase 2
SHIP-2
SHIP2
Background
The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodellin