Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human NTRK3. AA range:281-330
Subcellular Location
Membrane
Single-pass type I membrane protein.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
4916
Observed Band
95kD
Other Name
GP145-TrkC
NT-3 growth factor receptor
NTRK3
Neurotrophic tyrosine kinase receptor type 3
TRKC
Trk-C
TrkC tyrosine kinase
Background
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to