Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human CFLAR. AA range:1-50
Subcellular Location
cytoplasm,cytosol,death-inducing signaling complex,CD95 death-inducing signaling complex,membrane raft,ripoptosome,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
8837
Observed Band
55kD
Other Name
CASH
CASH
CASP8 and FADD-like apoptosis regulator
CASP8AP1
CFLAR
CLARP
CLARP
Caspase-eight-related protein
Caspase-like apoptosis regulatory protein
Caspase homolog
Casper
Cellular FLICE-like inhibitory protein
FADD-like antiapoptotic molecule 1
FLAME-1
I-FLICE
Inhibitor of FLICE
MACH-related inducer of toxicity
MRIT
MRIT
Usurpin
c-FLIP
CASH
CASP8 and FADD-like apoptosis regulator
CASP8AP1
CFLAR
CLARP
CLARP
Caspase-eight-related protein
Caspase-like apoptosis regulatory protein
Caspase homolog
Casper
Cellular FLICE-like inhibitory protein
FADD-like antiapoptotic molecule 1
FLAME-1
I-FLICE
Inhibitor of FLICE
MACH-related inducer of toxicity
MRIT
MRIT
Usurpin
c-FLIP
Background
The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encodin