Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human UCHL1. AA range:31-80
Subcellular Location
Cytoplasm . Endoplasmic reticulum membrane
Lipid-anchor . About 30% of total UCHL1 is associated with membranes in brain.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
7345
Observed Band
25kD
Other Name
Neuron cytoplasmic protein 9.5
PGP9.5
PGP 9.5
UCH-L1
UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1
Ubiquitin thioesterase L1
Background
The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neu