Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from DR3 . at AA range: 230-310
Subcellular Location
Single-pass type I membrane protein.
Single-pass type I membrane protein.
Single-pass type I membrane protein.
Single-pass type I membrane protein.
[Isoform 1]: Cell membrane
[Isoform 2]: Cell membrane
[Isoform 3]: Secreted.
[Isoform 4]: Secreted.
[Isoform 5]: Secreted.
[Isoform 6]: Secreted.
[Isoform 7]: Secreted.
[Isoform 8]: Secreted.
[Isoform 9]: Cell membrane
[Isoform 10]: Secreted.
[Isoform 11]: Cell membrane
[Isoform 12]: Secreted.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
8718
Observed Band
45kD
Other Name
APO3
Apo-3
Apoptosis-inducing receptor AIR
Apoptosis-mediating receptor DR3
Apoptosis-mediating receptor TRAMP
DDR3
DR3
Death receptor 3
LARD
Lymphocyte-associated receptor of death
Protein WSL
Protein WSL-1
TNFRSF12
TNFRSF25
Tumor necrosis factor receptor superfamily member 25
WSL
WSL1
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to st