Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the Internal region of human Smad5.
Subcellular Location
Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Rat
Human Gen
4090
Observed Band
52kD
Other Name
JV5-1
MADH5
MAD homolog 5
Mothers against DPP homolog 5
Mothers against decapentaplegic homolog 5
SMAD 5
SMAD5
SMAD family member 5
Smad5
hSmad5
Background
The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins typ