Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the C-terminal region of human NPRL2.
Subcellular Location
Lysosome membrane . Localization to lysosomes is amino acid-independent. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
10641
Observed Band
43kD
Other Name
G21 protein
Gene 21 protein
NPR2-like protein
NPRL2
Nitrogen permease regulator 2-like protein
TUSC4
Tumor suppressor candidate 4
Gene 21 protein
NPR2-like protein
NPRL2
Nitrogen permease regulator 2-like protein
TUSC4
Tumor suppressor candidate 4
Background
function:Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumo