Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the Internal region of human UHRF1.
Subcellular Location
Nucleus . Localizes to replication foci. Enriched in pericentric heterochromatin. Also localizes to euchromatic regions.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
29128
Observed Band
89kD
Other Name
E3 ubiquitin-protein ligase UHRF1
HuNp95
ICBP90
Inverted CCAAT box-binding protein of 90 kDa
NP95
Nuclear protein 95
Nuclear zinc finger protein Np95
RING finger protein 106
RNF106
Transcription factor ICBP90
UHRF1
Ubiquitin-like-containing PHD and RING finger domains protein 1
Ubiquitin-like PHD and RING finger domain-containing protein 1
hNp95
hUHRF1
HuNp95
ICBP90
Inverted CCAAT box-binding protein of 90 kDa
NP95
Nuclear protein 95
Nuclear zinc finger protein Np95
RING finger protein 106
RNF106
Transcription factor ICBP90
UHRF1
Ubiquitin-like-containing PHD and RING finger domains protein 1
Ubiquitin-like PHD and RING finger domain-containing protein 1
hNp95
hUHRF1
Background
This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2