Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the C-terminal region of human SNM1B.
Subcellular Location
Chromosome, telomere. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Mainly localizes to telomeres, recruited via its interaction with TERF2. During mitosis, localizes to the centrosome.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
64858
Observed Band
60kD
Other Name
5' exonuclease Apollo
DCLRE1B
DNA cross-link repair 1B protein
SNM1 homolog B
SNM1B
SNMIB
hSNM1B
DCLRE1B
DNA cross-link repair 1B protein
SNM1 homolog B
SNM1B
SNMIB
hSNM1B
Background
DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al.,