Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from Plk1 . at AA range: 80-160
Subcellular Location
Nucleus. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Midbody . localization at the centrosome starts at the G1/S transition (PubMed:24018379). During early st
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
5347
Observed Band
68kD
Other Name
PLK
PLK-1
PLK1
Polo-like kinase 1
STPK13
Serine/threonine-protein kinase 13
Serine/threonine-protein kinase PLK1
PLK-1
PLK1
Polo-like kinase 1
STPK13
Serine/threonine-protein kinase 13
Serine/threonine-protein kinase PLK1
Background
The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cel
hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015],
hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015],