Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Elmo1. AA range:22-71
Subcellular Location
Cytoplasm. Cell membrane. Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
9844
Observed Band
83kD
Other Name
ELMO1
Engulfment and cell motility protein 1
KIAA0281
Protein ced-12 homolog
Background
This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may