Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human WAVE1. AA range:91-140
Subcellular Location
Cytoplasm, cytoskeleton . Cell junction, synapse . Cell junction, focal adhesion . Dot-like pattern in the cytoplasm. Concentrated in Rac-regulated membrane-ruffling areas (PubMed:9889097). Partial translocation to focal adhesion sites might be mediated b
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
8936
Observed Band
70kD
Other Name
KIAA0269
Protein WAVE-1
SCAR1
Verprolin homology domain-containing protein 1
WASF1
WASP family protein member 1
WAVE1
Wiskott-Aldrich syndrome protein family member 1
Protein WAVE-1
SCAR1
Verprolin homology domain-containing protein 1
WASF1
WASP family protein member 1
WAVE1
Wiskott-Aldrich syndrome protein family member 1
Background
The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to