Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human EDD. AA range:1-50
Subcellular Location
Nucleus.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
51366
Observed Band
309kD
Other Name
E3 ubiquitin-protein ligase
E3 ubiquitin-protein ligase UBR5
EDD
EDD1
HECT domain-containing 1
HYD
Hyperplastic discs protein homolog
KIAA0896
Progestin-induced protein
UBR5
hHYD
Background
This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This