Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Tyrosinase. AA range:471-520
Subcellular Location
Melanosome membrane
Single-pass type I membrane protein . Melanosome . Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Human Gen
7299
Observed Band
80kD
Other Name
LB24-AB
Monophenol monooxygenase
SK29-AB
TYR
Tumor rejection antigen AB
Tyrosinase
Background
tyrosinase(TYR) Homo sapiens The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requ