Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human CADM1. AA range:393-442
Subcellular Location
Cell membrane
Single-pass type I membrane protein . Cell junction, synapse . Localized to the basolateral plasma membrane of epithelial cells in gall bladder. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
23705
Observed Band
49kD
Other Name
CADM1
Cell adhesion molecule 1
IGSF4
IGSF4A
IgSF4
Immunoglobulin superfamily member 4
NECL-2
NECL2
Nectin-like protein 2
SYNCAM
SgIgSF
Spermatogenic immunoglobulin superfamily
SynCAM
Synaptic cell adhesion molecule
TSLC1
Tumo
Background
disease:Absent or down-regulated in many advanced cases of NSCLC as well as in many other human cancers, due to gene silencing by promoter methylation.,domain:The cytoplasmic domain appears to play a critical role in proapoptosis and tumor suppressor acti