Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TRADD. AA range:251-300
Subcellular Location
Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Shuttles between the cytoplasm and the nucleus. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Mouse
Human Gen
8717
Observed Band
34kD
Other Name
TNFR1-associated DEATH domain protein
TNFRSF1A-associated via death domain
TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein
Background
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of i