Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TOP2A. AA range:1-50
Subcellular Location
Cytoplasm . Nucleus, nucleoplasm . Nucleus . Nucleus, nucleolus .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Human Gen
7153
Observed Band
174kD
Other Name
DNA topoisomerase 2-alpha
DNA topoisomerase II
TOP2
TOP2A
alpha isozyme
Background
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional str